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3.
Inmunología (1987) ; 30(3): 90-93, jul.-sept. 2011.
Artigo em Espanhol | IBECS | ID: ibc-108946

RESUMO

La fiebre Q es una zoonosis de distribución universal producida por Coxiella burnetti. La forma aguda de esta infección casi siempre produce afectación pulmonar y hepática en forma de neumonía y hepatitis a través del efecto directo de C. burnetti sobre los órganos afectados. Se describe en este trabajo la presencia de una hepatitis autoinmune y anticuerpos antifosfolípido como una complicación transitoria de esta infección. Estas manifestaciones son probablemente más frecuentes de lo que pensamos y probablemente estén infradiagnosticadas, por lo que consideramos que esta aportación clínica es importante para un conocimiento más profundo acerca de la fiebre Q y sus complicaciones (AU)


Q fever is a worldwide infection caused by Coxiella burnetti. The acute form of this condition usually produces pneumonia and hepatitis through the direct effect of Coxiella burnettion the involved organs. Here we describe the presence of autoimmune hepatitis and antiphospholipid antibodies as a transitory complication of this infection. These manifestations are probably more frequent than thought and they maybe underdiagnosed; so this report could be important for a deeper knowledge about Q fever and its complications (AU)


Assuntos
Humanos , Febre Q/complicações , Anticorpos Antifosfolipídeos/imunologia , Hepatite Autoimune/etiologia , Febre Q/imunologia , Coxiella burnetii/patogenicidade , Coxiella burnetii/imunologia , Inibidor de Coagulação do Lúpus
4.
Rev. clín. med. fam ; 2(4): 186-187, jun. 2008. ilus
Artigo em Es | IBECS | ID: ibc-69051

RESUMO

La ascariasis es la parasitosis más frecuente de todas las helmintiasis en humanos. Los efectos patológicosproducidos por los áscaris en el hombre se presentan en lugares diversos, de acuerdo con la localizaciónde sus distintas formas evolutivas. La ascariasis biliar en una de las complicaciones más severas.Presentamos un caso de pancreatitis aguda producida por infestación por Áscaris


Ascariasis is the commonest parasitosis of all human helminths. The pathological effects that ascaris producesin man manifest in different locations, in accordance with the location of its different evolutionaryforms. Biliary ascaris is one of the severest complications. We present a case of acute pancreatitis produced by Ascaris infestation


Assuntos
Humanos , Masculino , Adulto , Pancreatite Necrosante Aguda/parasitologia , Ascaris lumbricoides/patogenicidade , Ascaridíase/complicações
5.
Rev. clín. med. fam ; 2(3): 134-135, feb. 2008. ilus
Artigo em Es | IBECS | ID: ibc-69037

RESUMO

La nocardiosis es una enfermedad invasiva producida por especies del género Nocardia, bien a travésde la inhalación o la inoculación cutánea. Se presentan dos casos de neumonía por Nocardia en pacientes inmunodeprimidos


Nocardiosis is an invasive disease caused by the Norcardia species, either through inhalation orcutaneous inoculation. We report two cases of pneumonia caused by Norcadia in immunodepressed patients


Assuntos
Humanos , Masculino , Adulto , Idoso , Nocardiose/complicações , Pneumonia/microbiologia , Nocardia/patogenicidade , Hospedeiro Imunocomprometido , Infecções Oportunistas Relacionadas com a AIDS/microbiologia , Doença Pulmonar Obstrutiva Crônica/complicações
7.
Ren Fail ; 26(6): 613-8, 2004 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-15600251

RESUMO

Myoglobinuric acute renal failure has three pathogenic mechanisms: tubular obstruction, renal vasoconstriction, and oxidative stress. The latter is generated through the iron released from the group hemo of the myoglobin. Iron induces the formation of high-activity oxygen free radicals that increase oxidative stress and provoke lipid peroxidation and cellular death. This oxidative stress can be measured in several ways, both total or partially with the total antioxidant status or the intermediate enzymes. On the other hand, N-acetylcysteine is a demonstrated substance with antioxidant properties. The aim of the present work was to assess the effect of N-acetylcysteine on the oxidative stress in the glycerol-induced acute renal failure in rats model. We observed that the animals treated with N-acetylcysteine showed an improvement in the antioxidant activity given by an increase in the total antioxidant status and glutathione reductase levels in serum. This improvement was greater when treatment was administered before the induction of rhabdomyolysis. Nevertheless, the observed increase in antioxidant status was only statistically significant for glutathione reductase but not for total antioxidant status. Our results support an important role for N-acetylcysteine in the treatment of this form of acute renal failure, although we think that oxidative stress is not the main pathogenic mechanism of the tubular necrosis induced by rhabdomyolysis, tubular obstruction and renal vasoconstriction being still more important.


Assuntos
Acetilcisteína/farmacologia , Injúria Renal Aguda/tratamento farmacológico , Injúria Renal Aguda/patologia , Estresse Oxidativo/efeitos dos fármacos , Análise de Variância , Animais , Modelos Animais de Doenças , Feminino , Glicerol , Testes de Função Renal , Masculino , Estresse Oxidativo/fisiologia , Probabilidade , Distribuição Aleatória , Ratos , Ratos Sprague-Dawley , Valores de Referência , Sensibilidade e Especificidade
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